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As an alternative to Intubeaze® (20mg/ml lidocaine oral spray) during this period of unavailability we suggest that a formulation of plain lidocaine (without adrenaline) should be used in a 1 ml syringe, with an IV cannula (without the stylet) to help direct the lidocaine drops. The drops should be sprayed onto the arytenoid folds to achieve desensitisation of the larynx.

Visual assessment of feline airway. View of cat’s larynx with the mouth wide open and the cat in sternal recumbency and the same view in a clinical patient. 1 ml syringe being advanced over the top of the laryngeal opening and 0.2 ml of 2% lidocaine being dropped on to the top of the arytenoids. This will take 60–90 s to work so once the lidocaine has been applied, the cat should have oxygen provided until this time has elapsed. Journal of Feline Medicine and Surgery (2018) 20, 602–634.

A recent article investigating plasma concentrations after lidocaine drop/spray on the larynx combined with intra-testicular administration of lidocaine solution demonstrated a total dose of approximately 5 mg/kg appears to be safe for use in healthy adult cats.
Am J Vet Res. 2018 Jun;79(6):614-620.

Xylocaine spray is not a veterinary-licensed product and it must NOT be used in cats. From 1992 reports appeared regarding adverse effects following its use; it contains 10 mg/mL lidocaine in addition to other additivse such as ethanol, natural menthol and macrogol 400, essence of banana and saccharine. One of these additives is suspected of being responsible for adverse reactions such as laryngeal oedema characterized by stridor, respiratory distress and cyanotic mucous membranes, with some fatal outcomes in feline patients. 


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